- Direct synthesis of pentafluoroethyl copper from pentafluoropropionate as an economical C2F5 source: application to pentafluoroethylation of arylboronic acids and aryl bromides.
Direct synthesis of pentafluoroethyl copper from pentafluoropropionate as an economical C2F5 source: application to pentafluoroethylation of arylboronic acids and aryl bromides.
Organic letters (2014-06-14)
Hiroki Serizawa, Kohsuke Aikawa, Koichi Mikami
PMID24926803
초록
The direct synthesis of pentafluoroethyl copper (CuC2F5) from a cuprate reagent and ethyl pentafluoropropionate as one of the most economical and useful pentafluoroethyl sources was accomplished. The advantages of this method are; all the reagents employed are low-cost and operationally simple, and the CuC2F5 reagent is prepared in virtually quantitative yield. Furthermore, the CuC2F5 reagent prepared was successfully applied to two types of pentafluoroethylations with arylboronic acids and aryl bromides to provide the pentafluoroethylated aromatic products in good-to-excellent yields, including large scale operations.
MATERIALS
제품 번호
브랜드
제품 설명
Copper, wire reel, 20m, diameter 0.5mm, annealed, silver plated, 99.9%
Copper, wire reel, 500m, diameter 0.5mm, annealed, 99.9%
Copper, wire reel, 50m, diameter 0.25mm, as drawn, 99.99+%
Copper, tube, 1000mm, outside diameter 0.65mm, inside diameter 0.21mm, wall thickness 0.22mm, as drawn, 99.9%
Copper, sphere, 1000pcs, diameter 3.0mm, precision sphere grade 200
Copper, tube, 1000mm, outside diameter 0.75mm, inside diameter 0.23mm, wall thickness 0.26mm, as drawn, 99.9%
Copper, tube, 100mm, outside diameter 12.7mm, inside diameter 10.26mm, wall thickness 1.22mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 0.95mm, inside diameter 0.29mm, wall thickness 0.33mm, as drawn, 99.9%
Copper, sphere, 100pcs, diameter 3.0mm, precision sphere grade 200
Copper, tube, 1000mm, outside diameter 1.2mm, inside diameter 0.56mm, wall thickness 0.32mm, as drawn, 99.9%
Copper, rod, 100mm, diameter 16mm, as drawn, 99.99+%
Copper, tube, 1000mm, outside diameter 5.0mm, inside diameter 4mm, wall thickness 0.5mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 6.0mm, inside diameter 4mm, wall thickness 1.0mm, as drawn, 99.9%
Copper, tube, 100mm, outside diameter 0.75mm, inside diameter 0.23mm, wall thickness 0.26mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 1.0mm, inside diameter 0.24mm, wall thickness 0.38mm, as drawn, 99.9%
Copper, rod, 50mm, diameter 6.35mm, as drawn, 99.999%
Copper, tube, 100mm, outside diameter 1.75mm, inside diameter 0.33mm, wall thickness 0.71mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 12.7mm, inside diameter 10.26mm, wall thickness 1.22mm, as drawn, 99.9%
Copper, rod, 500mm, diameter 4.8mm, hard, 99.9%
Copper, rod, 100mm, diameter 6.35mm, as drawn, 99.999%
Copper, rod, 200mm, diameter 4.8mm, hard, 99.9%
Copper, rod, 200mm, diameter 9.5mm, hard, 99.9%
Copper, rod, 50mm, diameter 12.7mm, as drawn, 99.99+%