- Phosphine containing oligonucleotides for the development of metallodeoxyribozymes.
Phosphine containing oligonucleotides for the development of metallodeoxyribozymes.
Chemical communications (Cambridge, England) (2007-04-05)
Loïc Ropartz, Nico J Meeuwenoord, Gijsbert A van der Marel, Piet W N M van Leeuwen, Alexandra M Z Slawin, Paul C J Kamer
PMID17406706
초록
Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.
MATERIALS