Name: Gabapentin
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₉H₁₇NO₂

CAS Number:

60142-96-3

Molecular Weight:

171.24

Beilstein:

2359739

EC Number:

262-076-3

MDL number:

MFCD00865286

UNSPSC 코드:

12352200

PubChem Substance ID:

24278159

NACRES:

NA.77

기술 서비스

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도움 문의

Product Name

Gabapentin, solid

양식

solid

Quality Level

200

색상

off-white

solubility

H₂O: 10 mg/mL

SMILES string

NCC1(CC(O)=O)CCCCC1

InChI

1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)

InChI key

UGJMXCAKCUNAIE-UHFFFAOYSA-N

유전자 정보

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애플리케이션

Gabapentin has been used:

as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics
dissolved in uptake buffer which is used to measure the to measure ASP (trans-4-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide) substrate by organic cation transporter type 2 (OCTN2) using liquid chromatography - mass spectrometry
used as an analgesic adjuvant for intraperitoneal injections

생화학적/생리학적 작용

Anticonvulsant with unknown mechanism of action; crosses the blood brain barrier; increases GABA concentrations in the brain and reduces excitatory amino acid neurotransmission, perhaps through its effects on voltage-gated calcium channels; exhibits antinociceptive, anxiolytic, neuroprotective and anti-epileptic effects.

Gabapentin serves as a ligand for the α2δ subunit of L-type calcium channels.