Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics.

Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics.

Scientific reports (2016-11-04)

Bartosz Szczesny, Michela Marcatti, John R Zatarain, Nadiya Druzhyna, John E Wiktorowicz, Péter Nagy, Mark R Hellmich, Csaba Szabo

ABSTRACT

Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H

MATERIALS

Product Number

Brand

Product Description

Sigma-Aldrich

MISSION^® esiRNA, targeting human CTH

Sigma-Aldrich

MISSION^® esiRNA, targeting human CBS