S2002

Sodium azide

ReagentPlus^®, ≥99.5%

• Synonym(s): Hydrazoic acid sodium salt
• Linear Formula: NaN₃
• CAS Number: 26628-22-8
• Molecular Weight: 65.01
• EC Number: 247-852-1
• MDL number: MFCD00003536
• UNSPSC Code: 12352201
• PubChem Substance ID: 24899504
• NACRES: NA.21

Properties

• biological source: synthetic (inorganic)
• Quality Level: 200
• product line: ReagentPlus^®
• Assay: ≥99.5%
• form: powder
• storage condition: (Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)
• technique(s): cell based assay: suitable; immunohistochemistry: suitable
• color: white
• mp: 370-425 °C
• solubility: soluble 65 g/L at 20 °C (completely)
• suitability: suitable for chromatography; suitable for derivatization
• application(s): sample preparation
• SMILES string: [Na]N=[N+]=[N-]
• InChI: 1S/N3.Na/c1-3-2;/q-1;+1
• InChI key: PXIPVTKHYLBLMZ-UHFFFAOYSA-N

Description

General description

Sodium Azide (NaN3) is a potent inhibitor – a water-soluble crystalline powder that′s odorless. Widely recognized for its versatile applications, it plays a pivotal role across molecular biology, cell culture, and biochemical research. It is also a metabolic inhibitor, which inhibits oxidative phosphorylation. In cell culture, it maintains the integrity of your cell lines.

Application

Baylis-Hillman acetates such as ethyl 2-(acetoxyphenylmethyl)acrylate can undergo nucleophilic displacement by sodium azide in aqueous medium to form ethyl (E)-2-azidomethyl-3-phenylpropenoate.

Sodium azide is suitable for use in histopathology to prepare and store tissue samples. Also used as a component of staining buffer (HEPES buffer) for whole mount immunolabelling.
Catalyst for:

• Oxidative decarboxylation
• Michael addition reactions

Reagent for synthesis of

• Blue fluorescent copolymers
• Metal phosphonates
• Arenes via aminations

Biochem/physiol Actions

Sodium azide is clinically used as a preservative in diluting fluid for counting red blood cells. It prevents capping and internalization of fluorescent surface-bound antibodies in various scientific applications, including flow cytometry.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330,H373,H410
• Precautionary Statements: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• Target Organs: Brain
• Supplementary Hazards: EUH032
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable