Endotoxins are heat-stable lipopolysaccharide (LPS) and are components of the exterior cell wall of gram-negative bacteria. Bacteria shed endotoxin in large amounts upon cell death and when they are actively growing and dividing. Since endotoxins are pyrogenic in mammals, to ensure the safety of a patient, endotoxin content in the drug should always be controlled.
In this webinar, you will learn:
- Possible endotoxins contamination sources during manufacturing
- Ecologically sustainable methods of detecting endotoxins that do not involve animals
- Considerations for selecting raw materials for production
- Strategies for endotoxin removal
Speakers

Markus Greulich, Ph.D.
MilliporeSigma
Strategic Marketing Manager, Excipients Liquid Application
At MilliporeSigma, Markus is responsible for a broad portfolio of pharmaceutical excipients with a focus on regulatory topics. Prior to coming to MilliporeSigma, he worked in product development at RP Scherer/Catalent Pharma Solutions where he was responsible for formulation development and project management. Markus holds a Ph.D. in Pharmaceutical Sciences from the University of Heidelberg, Germany.

Subhasis Banerjee, Ph.D.
MilliporeSigma
Principal Bioprocessing Application Expert
Subhasis supports the technical consultation for downstream processing for the APAC region. He has a Ph.D. in biochemistry with post-doctoral experience from The Ohio State University, Columbus, USA. He has contributed to several publications in international peer-reviewed journals and conducted presentations in numerous national and international Conferences.

Brittany Gall
MilliporeSigma
Strategic Marketing Manager, Upstream Chemicals
Brittany leads global marketing activities for specialty chemicals used in upstream cell culture media at MilliporeSigma. She has been with MilliporeSigma for 13 years. Prior to joining the marketing franchise, Brittany worked in technical service, helping customers better understand how to use our products, and in the production lab as a chemist, manufacturing enzymes and proteins. Brittany holds a bachelor’s degree in biology from Florida State University.

Prateek Garg
MilliporeSigma
Global Segment Marketing Manager, Small Molecules
Prateek leads global marketing activities for key strategic segments of small molecules and therapeutic proteins. He has been with MilliporeSigma for 8 years and in the life science industry for well over a decade. Before moving to strategic marketing, Prateek had been working closely with customers as a sales manager, helping them choose the most optimal products for their formulation needs. He is a pharmacist, a business management graduate from NMIMS Mumbai, and has worked with BASF prior to joining our company.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:presented July 20, 2023
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