- A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
Organic letters (2014-06-17)
Xiaowen Xu, Min Zhang, Huanfeng Jiang, Jia Zheng, Yiqun Li
PMID24933098
ABSTRACT
A novel straightforward synthesis of both symmetrical and unsymmetrical 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF as a one-carbon synthon has been developed. The presented method allows synthesizing the products that are currently inaccessible or challenging to prepare with the advantages of operational simplicity, broad substrate scope, and no need for prefunctionalized reagents, making it a highly practical approach to access various 2,4-disubstituted-1,3,5-triazines.
MATERIALS
Product Number
Brand
Product Description
Copper, tube, 1000mm, outside diameter 0.75mm, inside diameter 0.23mm, wall thickness 0.26mm, as drawn, 99.9%
Copper, tube, 100mm, outside diameter 12.7mm, inside diameter 10.26mm, wall thickness 1.22mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 0.95mm, inside diameter 0.29mm, wall thickness 0.33mm, as drawn, 99.9%
Copper, sphere, 100pcs, diameter 3.0mm, precision sphere grade 200
Copper, tube, 1000mm, outside diameter 1.2mm, inside diameter 0.56mm, wall thickness 0.32mm, as drawn, 99.9%
Copper, sphere, 200pcs, diameter 3.0mm, precision sphere grade 200
Copper, tube, 1000mm, outside diameter 5.0mm, inside diameter 4mm, wall thickness 0.5mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 6.0mm, inside diameter 4mm, wall thickness 1.0mm, as drawn, 99.9%
Copper, tube, 100mm, outside diameter 0.75mm, inside diameter 0.23mm, wall thickness 0.26mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 1.0mm, inside diameter 0.24mm, wall thickness 0.38mm, as drawn, 99.9%
Copper, rod, 50mm, diameter 6.35mm, as drawn, 99.999%
Copper, tube, 100mm, outside diameter 1.75mm, inside diameter 0.33mm, wall thickness 0.71mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 12.7mm, inside diameter 10.26mm, wall thickness 1.22mm, as drawn, 99.9%
Copper, tube, 1000mm, outside diameter 0.65mm, inside diameter 0.21mm, wall thickness 0.22mm, as drawn, 99.9%
Copper, sphere, 1000pcs, diameter 3.0mm, precision sphere grade 200
Copper, rod, 500mm, diameter 4.8mm, hard, 99.9%
Copper, rod, 100mm, diameter 6.35mm, as drawn, 99.999%
Copper, rod, 200mm, diameter 4.8mm, hard, 99.9%
Copper, rod, 200mm, diameter 9.5mm, hard, 99.9%
Copper, rod, 50mm, diameter 12.7mm, as drawn, 99.99+%
Copper, rod, 100mm, diameter 16mm, as drawn, 99.99+%
Copper, insulated wire, 20m, conductor diameter 0.5mm, insulation thickness 0.06mm, polyimide insulation
Copper - O.F.H.C., foil, 300x1000mm, thickness 2.0mm, half hard, 99.95+%
Copper, insulated wire, 1m, conductor diameter 0.018mm, insulation thickness 0.005mm, polyurethane insulation, 99.99%
Copper - O.F.H.C., foil, 10m coil, thickness 0.025mm, hard, 99.95+%
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.05mm, coil width 300mm, half hard, 99.95+%
Copper, insulated wire, 50m, conductor diameter 0.125mm, insulation thickness 0.01mm, polyimide insulation, 99.99%
Copper, insulated wire, 20m, conductor diameter 0.125mm, insulation thickness 0.002mm, 2 micron polyesterimide insulation, 99.9%
Copper, microfoil, disks, 25mm, thinness 0.25μm, specific density 219.9μg/cm2, permanent mylar 3.5μm support, 99.99+%
Copper - O.F.H.C., foil, 50x50mm, thickness 0.1mm, half hard, 99.95+%