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EHU184131

Sigma-Aldrich

MISSION® esiRNA

targeting human SOX2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GTTTGCAAAAGGGGGAAAGTAGTTTGCTGCCTCTTTAAGACTAGGACTGAGAGAAAGAAGAGGAGAGAGAAAGAAAGGGAGAGAAGTTTGAGCCCCAGGCTTAAGCCTTTCCAAAAAATAATAATAACAATCATCGGCGGCGGCAGGATCGGCCAGAGGAGGAGGGAAGCGCTTTTTTTGATCCTGATTCCAGTTTGCCTCTCTCTTTTTTTCCCCCAAATTATTCTTCGCCTGATTTTCCTCGCGGAGCCCTGCGCTCCCGACACCCCCGCCCGCCTCCCCTCCTCCTCTCCCCCCGCCCGCGGGCCCCCCAAAGTCCCGGCCGGGCCGAGGGTCGGCGGCCGCCGGCGGGCCGGGCCCGCGCACAGCGCCCGCATGTACAACATGATGGAGACGGAGCTGAA

Ensembl | human accession no.

ENSG00000181449

NCBI accession no.

NM_003106

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... SOX2(6657) , Sox2()

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MISSION® esiRNA targeting human SOX2

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MISSION® esiRNA targeting human SOX9

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MISSION® esiRNA targeting human SNX2

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MISSION® esiRNA

Ensembl | human accession no.

ENSG00000181449

Ensembl | human accession no.

ENSG00000134532

Ensembl | human accession no.

ENSG00000125398

Ensembl | human accession no.

ENSG00000205302

esiRNA cDNA target sequence

GTTTGCAAAAGGGGGAAAGTAGTTTGCTGCCTCTTTAAGACTAGGACTGAGAGAAAGAAGAGGAGAGAGAAAGAAAGGGAGAGAAGTTTGAGCCCCAGGCTTAAGCCTTTCCAAAAAATAATAATAACAATCATCGGCGGCGGCAGGATCGGCCAGAGGAGGAGGGAAGCGCTTTTTTTGATCCTGATTCCAGTTTGCCTCTCTCTTTTTTTCCCCCAAATTATTCTTCGCCTGATTTTCCTCGCGGAGCCCTGCGCTCCCGACACCCCCGCCCGCCTCCCCTCCTCCTCTCCCCCCGCCCGCGGGCCCCCCAAAGTCCCGGCCGGGCCGAGGGTCGGCGGCCGCCGGCGGGCCGGGCCCGCGCACAGCGCCCGCATGTACAACATGATGGAGACGGAGCTGAA

esiRNA cDNA target sequence

CAAGGCAATCCAAGAAGCTCGGCAAATGAAGGAGCAACTCCGACGGGAACAACAGGTGCTTGATGGGAAGGTGGCTGTTGTGAATAGTCTGGGTCTCAATAACTGCCGAACAGAAAAGGAAAAAACAACACTGGAGAGTCTGACTCAGCAACTGGCAGTTAAACAGAATGAAGAAGGAAAATTTAGCCATGCAATGATGGATTTCAATCTGAGTGGAGATTCTGATGGAAGTGCTGGAGTCTCAGAGTCAAGAATTTATAGGGAATCCCGAGGGCGTGGTAGCAATGAACCCCACATAAAGCGTCCAATGAATGCCTTCATGGTGTGGGCTAAAGATGAACGGAGAAAGATCCTTCAAGCCTTTCCTGACATGCACAACTCCAACATCAGCAAGATATTGGGATCTCGCTGGA

esiRNA cDNA target sequence

ATCAAGACGGAGCAGCTGAGCCCCAGCCACTACAGCGAGCAGCAGCAGCACTCGCCCCAACAGATCGCCTACAGCCCCTTCAACCTCCCACACTACAGCCCCTCCTACCCGCCCATCACCCGCTCACAGTACGACTACACCGACCACCAGAACTCCAGCTCCTACTACAGCCACGCGGCAGGCCAGGGCACCGGCCTCTACTCCACCTTCACCTACATGAACCCCGCTCAGCGCCCCATGTACACCCCCATCGCCGACACCTCTGGGGTCCCTTCCATCCCGCAGACCCACAGCCCCCAGCACTGGGAACAACCCGTCTACACACAGCTCACTCGACCTTGAGGAGGCCTCCCACGAAGGGCGAAGATGGCCGAGATGATCCTAAAAATAACCGAAGAAAGAGAGGACCAACCAGAATTCCCT

esiRNA cDNA target sequence

GTTTCTTTGGACAGCCCTGAAAGGGAACCTATCCTATCCTCGGAACCTTCTCCTGCAGTCACACCTGTCACTCCTACTACACTCATTGCTCCTAGAATTGAATCAAAGAGTATGTCTGCTCCCGTGATCTTTGATAGATCCAGGGAAGAGATTGAAGAAGAAGCAAATGGAGACATTTTTGACATAGAAATTGGTGTATCAGATCCAGAAAAAGTTGGTGATGGCATGAATGCCTATATGGCATATAGAGTAACAACAAAGACATCTCTTTCCATGTTCAGTAAGAGTGAATTTTCAGTGAAAAGAAGATTCAGCGACTTTCTTGGTTTGCACAGCAAATTAGCAAGCAAATATTTACATGTTGGTTATATTGTGCCACCAGCTCCAGAAAAGAGTATAGTAGGGATGACCAAGGTCAAAG

Gene Information

human ... SOX2(6657), Sox2()

Gene Information

human ... SOX5(6660), SOX5(6660)

Gene Information

human ... SOX9(6662), SOX9(6662)

Gene Information

human ... SNX2(6643), SNX2(6643)

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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    Jiaxuan Chen et al.
    Molecular carcinogenesis, 56(10), 2267-2278 (2017-05-26)
    Fas signaling promotes colorectal cancer (CRC) metastasis by inducing epithelial-mesenchymal transition (EMT). The acquisition of EMT properties in turn induces stemness but the mechanism by which Fas signaling contributes to it still remains unclear. Hence, the aim of this study
    Liang Tang et al.
    Pathology oncology research : POR, 24(4), 907-913 (2018-04-06)
    Osteosarcoma (OS) was a prevalent malignant bone tumor which threatens people's health worldwide. Wnt/β catenin signaling pathway had been proved significant in various cancers, indicating its possible function in OS as well. Sox2, a crucial member among SOX family could
    Tatsuya Ishiguro et al.
    Cancer research, 76(1), 150-160 (2015-12-17)
    The establishment of cancer stem-like cell (CSC) culture systems may be instrumental in devising strategies to fight refractory cancers. Inhibition of the Rho kinase ROCK has been shown to favorably affect CSC spheroid cultures. In this study, we show how
    Keshav Gopal et al.
    Oncotarget, 7(3), 3111-3127 (2015-12-20)
    We have previously identified a novel intra-tumoral dichotomy in breast cancer based on the differential responsiveness to a Sox2 reporter (SRR2), with cells responsive to SRR2 (RR) being more stem-like than unresponsive cells (RU). Here, we report that RR cells
    Nicolas Chassaing et al.
    Genome research, 26(4), 474-485 (2016-02-20)
    Ocular developmental anomalies (ODA) such as anophthalmia/microphthalmia (AM) or anterior segment dysgenesis (ASD) have an estimated combined prevalence of 3.7 in 10,000 births. Mutations in SOX2 are the most frequent contributors to severe ODA, yet account for a minority of
    View All Related Papers

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