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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
2E2, monoclonal
species reactivity
rat
species reactivity (predicted by homology)
human (immunogen homology)
technique(s)
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ACE(1636)
General description
Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.
Immunogen
Human Angiotensin Converting Enzyme.
Application
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.
Quality
Evaluated by Western Blot in rat Angiotensin Converting Enzyme.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
Target description
~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.
Linkage
Replaces: MAB3502
Physical form
Mouse monoclonal IgG1 cultured supernatant without preservatives.
Analysis Note
Control
Rat Angiotensin Converting Enzyme
Rat Angiotensin Converting Enzyme
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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