POLD2
polymerase (DNA directed), delta 2, accessory subunit
Synonyms:
Species:
Human POLD2 (5425), Mouse Pold2 (18972), Rat Pold2 (289758), Thale Cress POLD2 (818812), Zebrafish pold2 (796456), domestic cat POLD2 (101095089), dog POLD2 (482686), chicken POLD2 (100859398), cow POLD2 (281991), sheep POLD2 (101117838) ...More
UniProtKB ID:
Gene ID:
- Human(5425) Summary: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]
- Mouse(18972) polymerase (DNA directed), delta 2, regulatory subunit
- Rat(289758) polymerase (DNA directed), delta 2, accessory subunit
- Thale Cress(818812) DNA polymerase delta subunit 2
- Zebrafish(796456) polymerase (DNA directed), delta 2, regulatory subunit
- domestic cat(101095089) polymerase (DNA directed), delta 2, accessory subunit
- dog(482686) polymerase (DNA directed), delta 2, accessory subunit
- chicken(100859398) polymerase (DNA directed), delta 2, accessory subunit
- cow(281991) polymerase (DNA directed), delta 2, regulatory subunit 50kDa
- sheep(101117838) polymerase (DNA directed), delta 2, accessory subunit
- domestic guinea pig(100727561) polymerase (DNA directed), delta 2, accessory subunit
- naked mole-rat(101722261) polymerase (DNA directed), delta 2, accessory subunit
- Domestic Rabbit(100358263) polymerase (DNA directed), delta 2, accessory subunit
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Small Molecule - Inhibitor
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